Experimental Alzheimer’s drug shows benefits in phase 3 trial, company says

2 comments

1. Alzheimer’s is a cruel disease I’m glad to see progress

2. I’m going to be very cautious about interpreting this. Aduhelm looked good in Stage III, got rushed through FDA approval and it, like a lot of other monoclonals to aB that have been investigated, has not really produced such great results.

   The amyloid hypothesis is very much under threat since the [alleged fabrications of Sylvain Lesne](https://www.science.org/content/article/potential-fabrication-research-images-threatens-key-theory-alzheimers-disease) have thrown it back into question. It’s looking more and more like treating amyloid plaques is just treating something downstream of the actual etiology.